Sr. Research Associate / Associate Scientist/ Sr. Associate Scientist - PE Department

Redmond, WA

About the position

We are seeking a talented Sr. Research Associate/ Associate Scientist / Senior Associate Scientist with extensive experience in antibody-based therapeutics, in Protein Engineering Department. The successful candidate will have a tracked record of molecular biology, protein purification and characterization, as well as cell culture.

Essential Duties and Responsibilities

  • Responsible for cloning, expression and characterization of protein constructs
  • Familiar with CHO/HEK expression systems.
  • Responsible for candidate optimization, selection, and validation.
  • Familiarity with AKTA (GE Healthcare) FPLC equipment along with a practical understanding of chromatographic principles.
  • Familiarity with HPLC ((Waters/Agilent system is a plus) equipment along with a practical understanding of chromatographic principles.
  • Write and review Standard Operating Procedures (SOP)
  • Familiarity with cancer cell culture experiment and assay method (ADCC/TDCC/RTCC is a plus)
  • Support and closely work with other divisions to advance company goals
  • Work with R&D and manufacturing department in China. Plan time to accommodate meetings and technical support with team members in China.
  • Able to manage timelines productively and bring projects to completion.
  • Other duties as assigned

Qualifications:

To perform this job successfully an individual must be able to perform each essential duty satisfactorily. The requirements listed below are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Education and Experience

  • MS or BS in Molecular Biology, Structural Biology, Chemistry, Biochemistry, Biophysical or a related field with 5 years (MS); 10 years (BS) of relevant academic and/or pharmaceutical or biotech experience.
  • Strong fundamental knowledge and experience in antibody structure, purification and engineering.
  • Extensive experience with cell culture system.
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