Principal Scientist - Antibody Discovery

Redmond, WA

Summary: We have an opportunity for a highly motivated Principal Scientist with expertise in antibody discovery to join our team in Redmond, WA. This position will contribute to the development of cancer therapeutics through the generation and selection of antibody candidates. This onsite, lab-based role will work closely with experienced scientists in a dynamic, fast-paced and highly collaborative environment.

Essential Duties and Responsibilities: 

Manage staff and contribute within the antibody discovery group, operating both established B cell culture, and yeast display-based antibody discovery platforms
Incorporate new methods and technologies toward immunogen engineering or compositions suited toward the therapeutic aims of each antibody campaigns
Use a variety of high throughput methods to characterize antibody biochemical, biophysical properties, functional and comparative features
Supervise antibody sequence rescue, sequencing and in silco analyses related to therapeutic developability
Expertly analyze experimental data and present scientific interpretation in group meetings
Cooperate with other R&D departments to utilize scientific and laboratory resources effectively
Develop strategies, identify priorities, establish timelines, to advance multiple discovery programs

Education/Experience 

PhD in Molecular Biology, Immunology, or related discipline with a minimum of 8 years of relevant experience, preferably in a biotech or pharmaceutical setting.
Background in B cell culture-based antibody discovery methods required. Experience using yeast libraries to generate therapeutic antibodies is a plus.
Expertise in screening and ranking of antibodies (ELISA, multi-parametric flow cytometry, BLI/OCTET).
Proven contribution to therapeutic antibody development and selection is highly desirable. Discovery of novel and biologically relevant antibodies highly desirable.

SystImmune is a stable, well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.

SystImmune is an Equal Opportunity Employer. Interested applicants should send their CV and cover letter to [email protected]