Scientist / Sr Scientist / Principal Scientist - Antibody Discovery

Redmond, WA

About the position

Located in Redmond WA, Systimmune Inc. is a bio-pharmaceutical company focused on the treatment of cancer through developing novel therapeutic multi-specific antibodies, as well as antibody-drug conjugates (ADC's). Our objective is to create biologics that work through systematic intervention on the solid tumor micro-environment, to either directly attack the tumor and/or to activate the immune system to attack the tumor. We are seeking a talented Scientist / Senior Scientist / Principal Scientist in developing Antibody Discovery Platform. The position requires strong interest in bench work and hands on in B cell culture experiments. Experience with immuno-oncology antibody discovery platform is plus.

Essential Duties and Responsibilities

  • Lead and participate in antibody discovery activities
  • In deep knowledge and experience in B cell culture is required
  • Independently develop immunization strategy and immunogen design
  • Hands on in B cell sorting and screening antibody for desire function
  • Strong background in B cell rescue, molecular biology and immuno-oncology
  • Use a variety of different assays to determine binding site mapping and competition analysis, specificity determination, kinetics and affinity determination
  • Ability to work in a high paced team environment, plan and meet timeline
  • Responsible to prioritize work on multiple projects, support and closely work with other divisions to advance company goals
  • Develop research plans, design experiments, outline research procedures to be followed, and identify or provides training to subordinate personnel to carry out research.
  • Knowledge of regulatory requirements. Write and review Standard Operating Procedures (SOP) and reports for regulatory filling.
  • Work with R&D department in China. Plan time to accommodate meetings and technical support
  • Participate in timeline planning and decision making regarding research priorities of company or department and provide information on feasibility of prospective projects.
  • Other duties as assigned.


Education and Experience
  • PhD in Immunology, cell biology, molecular biology or a related field with 4+ years of relevant academic and/or pharmaceutical or biotech experience
  • Hands on B cell culture and cell sorting experience is required
  • Strong scientific background of antibody discovery platform, with proven track record of IND filing, publications or presentations
  • Experience working with therapeutic antibodies and high throughput assays development is highly desirable
  • Experience with Octet and Flow Cytometry is plus
SystImmune is an Equal Opportunity Employer. Interested applicants should send their CV and cover letter to [email protected] Systimmune offers a flexible schedule, competitive salary, and generous benefits package, including a health/dental/vision care package, employer retirement match, and paid time off! Are you interested in this position? Apply now