Director Commercial Strategy, Iza-Bren
New Jersey
This role will report to the Executive Director, Commercial Strategy.
As the Director Commercial Strategy, Iza-Bren, you will be responsible for development, implementation and management of commercialization strategy for iza-bren, a first-in-class EGFR-HER3 bi-specific antibody drug conjugate being developed under a collaboration agreement with BMS. This role will drive cross-functional alignment across commercial, clinical, regulatory, alliance management functions within SystImmune and is critical in ensuring SystImmune’s vision for Iza-Bren is represented throughout all strategic and operational discussions with BMS.
This is an ideal role for a hands-on commercial leader with expertise in market analysis, forecasting, competitive intelligence, and cross-functional execution in oncology.
Key Responsibilities:
1. Commercial Execution for Izalontamab-Brengitecan
- Lead the development and execution of the commercialization strategy for Iza-Bren, ensuring alignment across SystImmune and alliance partner BMS.
- Own day-to-day commercial planning, including target product profile (TPP) refinement, competitive positioning, and market readiness activities.
- Work closely with clinical development teams (internal and alliance) to incorporate commercial insights into trial design and lifecycle planning.
- Co-create and support execution of medical advisory boards and thought leader engagements (TLEs) to ensure external perspectives inform strategy.
2. Market & Competitive Insights, Forecasting, and Commercial Analytics
- Conduct market research and landscape assessments to refine patient segmentation, uptake drivers, and barriers.
- Develop a competitive intelligence framework, monitoring key ADC competitors and identifying implications for brand strategy.
- Work closely with Finance and Business Development to develop and maintain revenue forecasts, ensuring alignment across internal and Alliance teams.
- Assess pricing and market dynamics, leveraging epidemiology data, analogs, and external insights to refine commercialization plans.
- Map out and prioritize key performance indicators (KPIs) for market readiness and stakeholder engagement, ensuring SystImmune’s strategic priorities are represented.
3. Cross-Functional & Alliance Collaboration for Market Preparation
- Work closely with Medical Affairs, Regulatory, Market Access, and other key functions (both internal and Alliance) to align commercialization efforts.
- Ensure SystImmune’s vision is recognized in all Alliance discussions and decision-making across commercial, clinical, and medical affairs teams.
- Support early-stage launch readiness planning, including defining key priorities for stakeholder engagement and market preparation efforts.
- Partner with Alliance teams to ensure cohesive strategic messaging, commercial positioning, and cross-functional coordination.
Qualifications:
- Advanced degree (MBA, PharmD, PhD, or equivalent) in business, life sciences, or a related field.
- 7+ years of related experience in biotech/pharmaceutical and/or life sciences consulting roles, including commercial strategy, forecasting, market research, brand planning, or portfolio management.
- Proven ability to collaborate across multiple functions, including clinical development, regulatory, medical affairs, finance, and market access, to align on commercialization strategies.
- Strong ability to analyze complex data and translate insights into strategic recommendations.
- Excellent communication and presentation skills across a variety of organization levels and functions including senior executives.
- Ability to influence and build effective relationships both within the organization and externally with alliance partners to drive projects and tasks towards completion.
- Prior experience in ADCs is a plus but not required; experience in oncology and/or specialty pharmaceuticals preferred.
- Experience working in an alliance or partnership setting is a plus.
The hiring pay range for this position is $180,000 - $250,000per year based on skills, education, and experience relevant to the role.
SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs).
SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials, SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discovery or IND-enabling stages, representing cutting-edge biologics development.
We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package.
SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply. To be considered, please send your CV and cover letter to [email protected]
